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UNDERSTANDING                      VACCINATION                                         The Midwest Cattleman · September 30, 2021 · P32
      continued from page 31             continued from page 17             events in a young calf’s life.       Option 1:  Branding and
                                                                            Research has shown that ad-       Weaning: requires the use of
      ther be culled or isolated and     cines used in this option be a     ministering vaccines during       two rounds of 5-way MLV re-
      treated and then re-tested six     MLV only.                          periods of high stress can be     spiratory vaccine (BVD 1 &
      months after treatment.               The effectiveness of a vac-     counterproductive  to the an-     2, IBR, PI3, and BRSV), re-
         In contrast, if your herd is    cine relies heavily on when        imal when compared to vac-        quires the use of two rounds
                                         vaccines are given. There are
      infected with anaplasmosis         many factors to consider that      cines given to animals not        of at least a 7-way clostridial
      and the organism is common         could positively or negatively     under stress. Utilizing a pre-    (blackleg) vaccine, and one
      in your area, a test-positive re-  impact the outcome such as         weaning or a delayed (a week      dose of M. haemolytica / P.
      placement animal is desired,       calf age, stress, and time be-     or two after weaning) vaccine     multocida (a.k.a. Shipping
      and the greatest health risk is    tween the first and second dose    administration may increase       fever) given at weaning.
      in  replacement  animals  that     of the vaccine. One example        efficacy and provide greater         Option 2: Preweaning and
      are not infected with the or-      deals with maternal antibody       protection to the animal.         Weaning: requires the use of
      ganism but that will be placed     interference (MAI). Colos-           The  time  period  between      two rounds of 5-way respira-
      in direct contact with carrier  tral antibodies received from         the 1st and 2nd dose of vac-      tory vaccine.  The first dose
                                                                            cines should also be consid-
      animals. In this situation, one  the dam at first milk provide        ered. Manufacturer require-       at preweaning may be MLV
      option is vaccination (if avail- the young calf with defense          ments on many commercial          or KV, with the second dose
      able) with close monitoring  mechanisms until the calf has            vaccines indicate that vaccine    at weaning being a MLV (re-
      for clinical signs of the disease  developed its own robust im-       doses be given 14 to 21 days      quired). Requires two rounds
      and quick treatment if disease  mune system. Research has             apart for the greatest disease    of at least a 7-way clostridial
      is detected.                       shown that vaccines given too      protection. Consult your vet-     vaccine, and one dose of M.
         Anaplasmosis control re- early in a young calf’s life may          erinarian to determine best       haemolytica  / P. multocida
      quires a good  working rela-       be perceived as a  “foreign”       practices for your operation.     given at weaning.
      tionship with your veterinari-     object by the maternal anti-                                            Option 3: Weaning  and
      an to determine your level of      bodies passed along to calf,  Vaccine product:                       Postweaning: Requires the
      risk and best control strate-      neutralizing the vaccine, and        The OQBN program al- use of two rounds of 5-way
      gies. The best control strategy    rendering it useless.              lows the use of KV and MLV  MLV  respiratory vaccine, re-
      for your herd may be very dif-        For vaccines to work most  vaccines with certain timing  quires the use of two rounds
      ferent from that of your neigh-    effectively, the calf should  strategies for administration.  of at least a 7-way clostridial
                                         be healthy  and unstressed.  Producers may request al- vaccine, and one dose of M.
      bors or cattlemen in other         Stress is considered the num- ternative plans for review by  haemolytica  / P. multocida
      parts of the country.              ber one precursor to disease in  OQBN administrators only  given at either weaning or
                                         livestock animals,  and wean- with significant cause and  postweaning
                                         ing is one of the most stressful  justification.
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