Page 20 - MWC 4-21-2022s

Managing Replacement Heifers - Reproductive Tract Scoring
Approved by FDA under NADA # 141-143 The Midwest Cattleman · April 21, 2022 · P20
Noromycin ®
300 LA By Mark Z. Johnson, OSU Extension Beef Cattle Breeding Specialist
(oxytetracycline injection)
ANTIBIOTIC
Reproductive Tract Scor-
Each mL contains 300 mg of oxytetracycline base ing (RTS) is a management
(equivalent to 323.5 mg of oxytetracycline
tool available to producers
dihydrate).
For Use in Beef Cattle, Non-lactating Dairy Cattle,
Calves, Including pre-ruminating (veal) calves currently making selection
BRIEF SUMMARY (For full Prescribing decisions on yearling heif-
Information, see package insert.) ers. RTS is a subjective mea-
INDICATIONS:
NOROMYCIN 300 LA is intended for use in surement which involves the
treatment for the following diseases when due to
oxytetracycline-susceptible organisms: rectal palpation of the heifer
Beef cattle, non-lactating dairy cattle, calves, reproductive tract (uterine
including pre-ruminating (veal) calves:
NOROMYCIN 300 LA is indicated in the treatment horns and ovarian struc-
of pneumonia and shipping fever complex
associated with Pasteurella spp., and Histophilus tures) and the subsequent
spp. NOROMYCIN 300 LA is indicated for the
treatment of infectious bovine assignment of a reproductive
keratoconjunctivitis (pink eye) caused by
Moraxella bovis, foot-rot and diphtheria caused tract score, ranging from 1 to
by Fusobacterium necrophorum; bacterial
enteritis (scours) caused by Escherichia coli; 5 (1 = immature; 5 = presence
wooden tongue caused by Actinobacillus
lignieresii; leptospirosis caused by Leptospira of a corpus luteum), to assist
pomona; and wound infections and acute metritis
caused by strains of staphylococcal and the producer in making re- if they do become pregnant, Another possible applica-
streptococcal organisms sensitive to
oxytetracycline. do so later in the breeding tion of the RTS system is to
placement heifer decisions.
Swine: season suggesting that heif- assess the nutritional pro-
NOROMYCIN 300 LA is indicated in the treatment Since age at puberty is
of bacterial enteritis (scours, colibacillosis) ers with a RTS of 1 should gram being utilized by the
caused by Escherichia coli; pneumonia caused difficult to measure directly,
by Pasteurella multocida; and leptospirosis possibly be eliminated from producer. If RTS is taken
caused by Leptospira pomona. RTS can estimate pubertal
In sows NOROMYCIN 300 LA is indicated as an status, and if performed be- the breeding group. It is within a sufficient time be-
aid in control of infectious enteritis (baby pig
scours, colibacillosis) in suckling pigs caused by fore the onset of the breeding worth mentioning that some fore the start of the breeding
Escherichia coli. heifers do not exactly fit a season (approximately 30 to
PRECAUTIONS: season, can be a predictor of
Exceeding the highest recommended level of heifer reproductive perfor- particular RTS score, and it 60 days); based on the re-
drug per pound of bodyweight per day,
administering more than the recommended mance allowing for heifers is up to the producer and/ sults of the tract scores, the
number of treatments, and/or exceeding 10 mL
intramuscularly or subcutaneously per injection with a poor breeding poten- or practitioner to decide on producer can adjust the ra-
site in adult beef cattle and non-lactating dairy
cattle and 5 mL intramuscularly per injection site tial to be removed from the which of the measures are to tion to help the heifers reach
in adult swine, may result in antibiotic residues
beyond the withdrawal time. breeding group before any be given the most emphasis. developmental goals prior to
Consult with your veterinarian prior to RTS should be done about the beginning of the breed-
administering this product in order to determine further costs are incurred.
the proper treatment required in the event of an A RTS score of 1 refers to a 1 month or less prior to ing season or the beginning
adverse reaction. At the first sign of any adverse
reaction, discontinue use of the product and seek breeding if the score is to be of the breeding season can be
the advice of your veterinarian. Some of the prepubertal heifer, a RTS of
reactions may be attributable either to used as a culling tool as an adjusted.
anaphylaxis (an allergic reaction) or to 2 or 3 refers to a peripubertal
cardiovascular collapse of unknown cause. heifer (transitional stage), indicator of a heifer's ability If your heifers are a little
Shortly after injection treated animals may have to conceive early during the behind schedule this spring,
transient hemoglobinuria resulting in darkened and a RTS of 4 or 5 refers to a
urine. pubertal (cycling) heifer. The first breeding season. If RTS consult with your Veterinar-
As with all antibiotic preparations, use of this
drug may result in overgrowth of non-susceptible reproductive performance of is to be used as a selection ian about RTS. It can be in-
organisms, including fungi. The absence of a
favorable response following treatment, or the heifers with an RTS of 1 or tool to place pressure on age formative and beneficial in
development of new signs or symptoms may
suggest an overgrowth of non-susceptible 2 is less than that of heifers at puberty, the best time to the selection process of year-
organisms. If superinfections occur, the use of
this product should be discontinued and with an RTS of 3 or greater. evaluate the heifers is when ling replacement heifers.
appropriate specific therapy should be instituted. approximately 50% of the Reference: Stein, Dan. Re-
Since bacteriostatic drugs may interfere with the Heifers with a RTS of 1 or 2
bactericidal action of penicillin, it is advisable to are less likely to be cycling at heifers are thought to be cy- productive Tract Scoring,
avoid giving NOROMYCIN 300 LA in conjunction
with penicillin. the beginning of the breeding cling based on age, weight, Cow-Calf Corner, May 2021.
season and therefore are less
WARNINGS: and occasional observations
Warnings: Discontinue treatment at for estrus.
least 28 days prior to slaughter of cattle likely to become pregnant or
and swine. Not for use in lactating
dairy animals. Rapid intravenous
administration may result in animal
collapse. Oxytetracycline should be
administered intravenously slowly over
a period of at least 5 minutes.
CAUTION:
Intramuscular or subcutaneous injection may
result in local tissue reactions which persists
beyond the slaughter withdrawal period.
This may result in trim loss of edible tissue at
slaughter.
Intramuscular injection in the rump area may
cause mild temporary lameness associated with
swelling at the injection site. Subcutaneous
injection in the neck area may cause swelling at
the injection site.
ADVERSE REACTIONS:
Reports of adverse reactions associated with
oxytetracycline administration include injection
site swelling, restlessness, ataxia, trembling,
swelling of eyelids, ears, muzzle, anus and vulva
(or scrotum and sheath in males), respiratory
abnormalities (labored breathing), frothing at the
mouth, collapse and possibly death. Some of
these reactions may be attributed either to
anaphylaxis (an allergic reaction) or to
cardiovascular collapse of unknown cause.
To report a suspected adverse reaction call
1-866-591-5777.
Livestock Drug - Not for Human Use.
Restricted Drug(s) California. Use Only as
Directed.
Manufactured by:
Norbrook, Inc.
Lenexa, KS 66219
MADE IN THE UK
Rev: August 2021
Version: I08