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COULD CATTLE The Midwest Cattleman · September 14, 2023 · P14
Tulieve continued from page 12
®
(tulathromycin injection)
Injectable Solution from the survey. And the ex-
Antibiotic pected corn prices in the next
100 mg of tulathromycin/mL 18 months ahead over the last
For use in beef cattle (including suckling calves), non-lactating dairy cattle
(including dairy calves), veal calves, and swine. Not for use in female dairy three surveys certainly show
cattle 20 months of age or older. a downward trend in what
CAUTION: Federal (USA) law restricts this drug use by or on the order of a
licensed veterinarian. folks expect on the corn side,"
DESCRIPTION: says Brown.
Tulieve® Injectable Solution is a ready-to-use sterile parenteral preparation
containing tulathromycin, a semi-synthetic macrolide antibiotic of the Economists say the biggest
subclass triamilide. Each mL of Tulieve contains 100 mg of tulathromycin, impacts on crop prices will
500 mg propylene glycol, 19.2 mg citric acid and 5 mg monothioglycerol.
Sodium hydroxide or hydrochloric acid may be added to adjust pH. come from:
Tulieve consists of an equilibrated mixture of two isomeric forms of
tulathromycin in a 9:1 ratio. •Demand domestically (in-
The chemical names of the isomers are (2R,3S,4R,5R,8R,10R,11R,12S,13S, cluding for feed grains) and
14R)-13-[[2,6-dideoxy-3-C-methyl-3-Ο-methyl-4-C-[(propylamino) methyl]-
α-L-ribo-hexopyrano-syl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14- abroad (particularly in China)
hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]- commodities, the ag economy sponded to the question.
oxy]-1-oxa-6-azacyclopentadecan-15-one and (2R,3R,6R,8R,9R,10S,11S, •War in the Black Sea if
12R)-11-[[2,6-dideoxy-3-C-methyl-3-Ο-methyl-4-C-[(propylamino)methyl]- has been resilient." "The current most-import-
α-L-ribo-hexopyrano-syl]oxy]-2-[(1R,2R)-1,2-dihydroxy-1-methylbutyl]- shipments from Russia are ant factors are weather and
8-hydroxy-3,6,8,10,12-pentamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-
β-D-xylo-hexopyranosyl]oxy]-1-oxa-4- azacyclotridecan-13-one, respectively. curtailed What Will Drive the Ag input costs. In one year from
INDICATIONS •El Nino presence and
Beef and Non-Lactating Dairy Cattle Economy Over the Next 12 now, it will be Brazilian pro-
BRD-Tulieve Injectable Solution is indicated for the treatment of bovine weather in major crop produc- Months? duction policy," says another
respiratory disease (BRD) associated with Mannheimia haemolytica, tion areas of the world
Pasteurella multocida, Histophilus somni, and Mycoplasma bovis; and for the The economists turned economist.
control of respiratory disease in cattle at high risk of developing BRD •Strong competition in
associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus more bullish on livestock in "Agriculture is benefiting
somni, and Mycoplasma bovis. the international corn export
IBK-Tulieve Injectable Solution is indicated for the treatment of infectious the latest survey, while the from somewhat lower input
bovine keratoconjunctivitis (IBK) associated with Moraxella bovis. market and U.S. export levels outlook for corn prices pro- prices, but weather is creat-
Foot Rot-Tulieve Injectable Solution is indicated for the treatment of •U.S. crop acreage stable,
bovine foot rot (interdigital necrobacillosis) associated with Fusobacterium duced more pessimism. But ing challenges in production.
necrophorum and Porphyromonas levii. better yields pushing down
Suckling Calves, Dairy Calves, and Veal Calves economists continue to be im- During the next 12 months
BRD-Tulieve Injectable Solution is indicated for the treatment of BRD prices
associated with M. haemolytica, P. multocida, H. somni, and M. bovis. pressed with how farmers and production costs should con-
Swine ranchers have withstood high- tinue to moderate, but prices
Tulieve Injectable Solution is indicated for the treatment of swine Overall Outlook for the Ag
respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, er costs on their operation. are also moderating so that
Pasteurella multocida, Bordetella bronchiseptica, Haemophilus parasuis, and Economy
Mycoplasma hyopneumoniae; and for the control of SRD associated with "The financial strength on the net change is slightly pos-
Actinobacillus pleuropneumoniae, Pasteurella multocida, and Mycoplasma Brown says the month- many farms is rather strong itive. A new farm bill needs to
hyopneumoniae in groups of pigs where SRD has been diagnosed. ly survey shows economists'
DOSAGE AND ADMINISTRATION and many have taken advan- be completed to create more
Cattle views of the ag economy ha-
Inject subcutaneously as a single dose in the neck at a dosage of 2.5 mg/kg tage of relatively high pric- certainty and reduce reve-
(1.1 mL/100 lb) bodyweight (BW). Do not inject more than 10 mL per ven't changed much in the es for crops and cattle. Hogs nue risk," is another response
injection site. three months of conducting
Swine and poultry are in somewhat from the anonymous survey.
Inject intramuscularly as a single dose in the neck at a dosage of 2.5 mg/kg the survey. The August data
(0.25 mL/22 lb) BW. Do not inject more than 2.5 mL per injection site. worse shape now than last
CONTRAINDICATIONS show economists are: year. Looking ahead, I expect Projecting the Positives
The use of Tulieve Injectable Solution is contraindicated in animals •5% less optimistic about
previously found to be hypersensitive to the drug. that lower crop prices and Pieces for the Ag Economy
WARNINGS the health of the ag economy stable input prices will put a With so much concern about
FOR USE IN ANIMALS ONLY. a year from now relative to
NOT FOR HUMAN USE. squeeze on high-cost crop pro- international competition and
KEEP OUT OF REACH OF CHILDREN. today
NOT FOR USE IN CHICKENS OR TURKEYS. ducers. Consolidation across domestic demand, economists
RESIDUE WARNINGS •10% less optimistic when all of agriculture is something also pointed out some posi-
Cattle looking at the ag economy
Cattle intended for human consumption must not be slaughtered I expect to be a theme in the tives in the ag economy, in-
within 18 days from the last treatment. This drug is not approved for today versus 12 months ago year ahead," says one ag econ- cluding farmland values and
use in female dairy cattle 20 months of age or older, including dry
dairy cows. Use in these cattle may cause drug residues in milk and/or "I think the biggest thing omist in the anonymous sur- the U.S. economy.
in calves born to these cows. to note is just how resilient
Swine vey. •"The land value market
Swine intended for human consumption must not be slaughtered we've been. And that shows
within 5 days from the last treatment. "We're seeing an explosion has a lot of supportive fun-
PRECAUTIONS in some of the answers we got of competitive production damentals under it and will
Cattle back from the economists,"
The e ects of tulathromycin injection on bovine reproductive performance, coming out of Brazil at the withstand a couple years of
pregnancy, and lactation have not been determined. Subcutaneous says Brown. "Although there's same time that geopolitical negative farm income. As a re-
injection can cause a transient local tissue reaction that may result in trim
loss of edible tissue at slaughter. been lots of concern about con- risks are increasing in a world sult, farm balance sheets will
Swine sumer demand and interna-
The e ects of tulathromycin injection on porcine reproductive performance, facing mounting credit risks," stay rather healthy and those
pregnancy, and lactation have not been determined. Intramuscular tional demand for a lot of our
injection can cause a transient local tissue reaction that may result in trim was how one economist re- that have available working
loss of edible tissue at slaughter. capital and cash will be posi-
ADVERSE REACTIONS
Cattle tioned well," says one econo-
In one BRD eld study, two calves treated with tulathromycin injection at mist.
2.5 mg/kg BW exhibited transient hypersalivation. One of these calves also
exhibited transient dyspnea, which may have been related to pneumonia. •"At least so far, the U.S.
Swine
In one eld study, one out of 40 pigs treated with tulathromycin injection at economy has proven more re-
2.5 mg/kg BW exhibited mild salivation that resolved in less than four hours. silient in 2023 than many had
Approved by FDA under ANADA # 200-723 anticipated," was another re-
Tulieve® is a registered trademark of Norbrook Laboratories Limited
Made in the UK sponse in the monthly survey.
Manufactured by: •"Lower fertilizer costs and
Norbrook Laboratories Limited, Newry, BT35 6PU, Co. Down,
Northern Ireland a relatively stable U.S. econo-
To report suspected adverse drug events, for technical assistance or to my," says another economist.
obtain a copy of the Safety Data Sheet (SDS), contact Norbrook at
1-866-591-5777. For additional information about adverse drug •"I see strong international
experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or
http://www.fda.gov/reportanimalae. markets for pork and beef as
Revised Feb 2022 the most positive aspect re-
For additional Tulieve garding the outlook of U.S. ag-
product information call:
1-866-591-5777 or go to riculture," one economist says.
NorbrookFA.com/Tulieve
Drovers